Original Article: Effect of Comprehensive Diabetes Care on Glycaemic Control with Reduction in Dependency of Oral Hypoglycaemic Medicines in Pre-obese Diabetic Patients: A Retrospective Study
Journal: International Journal of Current Research and Academic Review
Clinical Study: Int.J.Curr.Res.Aca.Rev.2018; 6(11): 73-81
Journal Published Link: http://www.ijcrar.com/6-11-2018/Rohit%20Sane,%20et%20al.pdf
Although multiple new drugs are coming out in the market, India has the 2nd highest number of diabetics in the world.The aim of this study was to evaluate effects of Comprehensive Diabetes Care (CDC) on Glycosylated haemoglobin (HbA1c) and metabolic parameters in pre-obese diabetic patients. In this retrospective study, data of pre-obese DM patients who had received 6 CDC sittings over 90 days in the out-patient departments (OPDs) at Madhavbaug clinics was collected between May 2013 to April 2018. Demographic and co-morbidity details were noted. HbA1c, body mass index (BMI), abdominal girth, systolic and diastolic blood pressure (SBP, DBP), dependency on medications were assessed on days 1 and 90 of CDC. The patients followed a specific low-calorie diet plan during the study. 89 participants, (52 males, 37 females) were enrolled. Mean HbA1c measured at day 90 was significantly lower than that on day 1 (6.86 ± 1.24 vs 9.02 ± 1.79, p<0.001). Mean BMI was significantly reduced on day 90 when compared to baseline (25.39 ± 1.53 vs 27.24 ± 1.33, p<0.001). Abdominal girth was significantly decreased on day 90 compared to baseline (91.64 ± 6.26 vs 97.12 ± 7.03, p<0.001). SBP (122.83 ± 13.56 vs 131.60 ± 16.10, p<0.001) and DBP (77.02 ± 6.81 vs 81.75 ± 9.43, p<0.001) were also significantly decreased after 90 days. Dependency on concomitant medicines was reduced. Glycaemic control and metabolic parameters significantly improved after 90-day CDC treatment. Reduction in blood pressure and intake of concomitant medications were also noted.
Keywords: Comprehensive diabetes care, CDC, Panchakarma, Diabetes mellitus, HbA1c, Body mass index, Ayurveda, Alternative medicine