Madhavbaug http://madhavbaug.org Wed, 13 Nov 2019 07:51:12 +0000 en-US hourly 1 https://wordpress.org/?v=5.1.3 Efficacy Of Comprehensive Diabetes Care (CDC) Management Program In Elderly Male Patients Of Type II Diabetes Mellitus: A Retrospective Study http://madhavbaug.org/efficacy-of-comprehensive-diabetes-care-cdc-management-program-in-elderly-male-patients-of-type-ii-diabetes-mellitus-a-retrospective-study/ http://madhavbaug.org/efficacy-of-comprehensive-diabetes-care-cdc-management-program-in-elderly-male-patients-of-type-ii-diabetes-mellitus-a-retrospective-study/#respond Thu, 07 Mar 2019 08:04:16 +0000 http://madhavbaug.org/?p=7523 The post Efficacy Of Comprehensive Diabetes Care (CDC) Management Program In Elderly Male Patients Of Type II Diabetes Mellitus: A Retrospective Study appeared first on Madhavbaug.

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Original Article: Efficacy Of Comprehensive Diabetes Care (CDC) Management Program In Elderly Male Patients Of Type II Diabetes Mellitus: A Retrospective Study

Journal: International Journal of Diabetes and Endocrinology

Clinical Study: 2018; 3(2): 29-34

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Journal Published Link: http://www.sciencepublishinggroup.com/journal/index?journalid=278

Abstract

Globally, Diabetes mellitus (DM) prevalence has created menace, being a major culprit of increased mortality and morbidity and health care expenditures. India is the 2nd country with maximum number of diabetic patients, with an estimated prevalence of around 10%. Comprehensive Diabetes Care (CDC) is a combination of Panchakarma and Diet management. This study was conducted to evaluate the effect of CDC on glycosylated haemoglobin (HbA1c), body mass index (BMI), body weight, abdominal girth and dependency on conventional therapy in DM Patients. This retrospective study was conducted from July 2017 to January 2018, wherein the data of elderly male type 2 DM patients (HbA1c >6.5%) who attended Madhavbaug clinics in Maharashtra, India were identified. Data of patients who were administered CDC (60-75 minutes) with minimum 6 sittings over 90 days (± 15 days) were considered. Variables were compared between day 1 and day 90 of CDC. Out of 48 enrolled elderly male patients, 34 were included for analysis. CDC showed significant improvement in HbA1c from 8.27 ± 0.96to 7.1 ± 1.30; p=0.0001), BMI from 27.65 ± 3.20 to 25.91 ± 3.29, p< 0.0001), weight from 73.75 ± 10.76to 69.46 ± 10.39, p<0.0001). Abdominal girth (from 100.0 ± 9.08 to 95.36 ± 9.10; p<0.0001), also showed significant reduction. Dependency on concomitant medicines was reduced, with number of patients on no concomitant medicines increasing from 3% to 15%. CDC and allopathy both are found to be efficacious; but CDC acts dually, by reducing HbA1c, as well as reducing dependency on allopathic medications.

Keywords: Comprehensive Diabetes Care, CDC, Panchakarma, HbA1C, BMI, DM, Alternative Medicine

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To Study Efficacy of Comprehensive Diabetes Care (CDC) Management Program in Type II Diabetic Obese Patients: An Observational Study http://madhavbaug.org/to-study-efficacy-of-comprehensive-diabetes-care-cdc-management-program-in-type-ii-diabetic-obese-patients-an-observational-study/ http://madhavbaug.org/to-study-efficacy-of-comprehensive-diabetes-care-cdc-management-program-in-type-ii-diabetic-obese-patients-an-observational-study/#respond Thu, 07 Mar 2019 07:54:51 +0000 http://madhavbaug.org/?p=7520 The post To Study Efficacy of Comprehensive Diabetes Care (CDC) Management Program in Type II Diabetic Obese Patients: An Observational Study appeared first on Madhavbaug.

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Original Article: To Study Efficacy of Comprehensive Diabetes Care (CDC) Management Program in Type II Diabetic Obese Patients: An Observational Study

Journal: International Journal of Ayurveda and Pharma research.

Clinical Study: IJAPR | June 2018 | Vol 6 | Issue 6

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Journal Published Link: https://ijapr.in/index.php/ijapr/article/view/937

Abstract

Context: Diabetes mellitus (DM) contributes to a major chunk of morbidity, mortality, and healthcare cost on a global level. The prevalence of DM is rising alarmingly, worldwide and India. Comprehensive Diabetes Care (CDC) is a combination of Panchakarma and diet management.

Aims: This study was conducted to evaluate the effect of CDC on Glycosylated hemoglobin (HbA1c), body mass index (BMI), body weight, abdominal girth and dependency on conventional therapy in DM Patients.

Setting and Design: This observational study was conducted in July 2017, wherein the data of obese Type II DM patients (HbA1c >6.5%) who attended out-patient departments (OPDs) at Madhavbaug clinics in Maharashtra, India were identified.

Materials and Methods: Data of patients who were administered CDC (60-75 minutes) with minimum 6 sittings over 90 days (± 15 days) were considered. Variables were compared between day 1 and day 90 of CDC.

Results: Out of 27 patients, 22 were included for analysis, out of which 10 were males while 12 females. CDC showed significant improvement in HbA1c 1.1% (from 8.80 ± 0.93 to 6.98 ± 1.73; p<0.001), BMI by 2.66 (from 33.79 ± 3.80 to 31.13 ± 3.91, p< 0.001), weight by 6.56 kg (from 83.67 ± 11.28 to 77.11 ± 12.27, p<0.001). Abdominal girth (from 104.34 ± 9.74 to 96.97 ± 11.93; p<0.001), also showed significant reduction. Dependency on concomitant medicines was reduced, with the number of patients on no concomitant medicines increasing from 27% to 41%.

Conclusion: Comprehensive Diabetes Care Management Program found to be efficacious; by reducing HbA1c, as well as reducing dependency on allopathic medications.

KEYWORDS: Comprehensive Diabetes Care, CDC, Panchakarma, Glycosylated HB, HbA1C, BMI, DM, Alternative Medicine.

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To Study Efficacy Of Blood Pressure Management Program (BPMP) In Male Elderly Patients With Known Case Of Hypertension: An Observational Study http://madhavbaug.org/to-study-efficacy-of-blood-pressure-management-program-bpmp-in-male-elderly-patients-with-known-case-of-hypertension-an-observational-study/ http://madhavbaug.org/to-study-efficacy-of-blood-pressure-management-program-bpmp-in-male-elderly-patients-with-known-case-of-hypertension-an-observational-study/#respond Thu, 07 Mar 2019 07:36:46 +0000 http://madhavbaug.org/?p=7515 The post To Study Efficacy Of Blood Pressure Management Program (BPMP) In Male Elderly Patients With Known Case Of Hypertension: An Observational Study appeared first on Madhavbaug.

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Original Article: To Study Efficacy Of Blood Pressure Management Program (BPMP) In Male Elderly Patients With Known Case Of Hypertension: An Observational Study

Journal: Cardiology and Cardiovascular Research

Clinical Study: Volume 3, Issue 1, March 2019

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Journal Published Link: http://www.sciencepublishinggroup.com/journal/index?journalid=279

Abstract

Around 20% of the population are in prehypertension stage, and nearly 40% of the adult population from Hypertension (HTN). Blood Pressure Management Program (BPMP) is an Ayurvedic treatment strategy using Panchakarma. This study was conducted to evaluate the effect of BPMP on systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), body mass index (BMI) and dependency on conventional therapy in elderly male patients of HTN. This observational study was conducted from January 2017 to February 2018, wherein the data of HTN patients who attended Madhavbaug clinics in Maharashtra, India were identified. Data of patients who were administered BPMP (60-75 minutes) with minimum 6 sittings over 90 days (± 15 days) were considered. Variables were compared between day 1 and day 90 of BPMP. Out of 29 enrolled patients, 24 were finally selected for analysis. BPMP showed significant improvement in SBP by 24.66 (from 150.67 ±12.97 to 126 ± 13.01; p<0.001), DBP by 10.8 (from 87.7917 ±7.72 to 76.917 ±7.59, p< 0.001), MAP by 15.4 (from 108.75 ±7.14 to 93.25 ±8.72, p<0.001). BMI (25.7275 ±2.63 kg/m2 to 24.91 ±2.32 kg/m2), also showed significant reduction. Dependency on concomitant medicines was reduced, with the number of patients on no concomitant medicines increasing from 19% to 29%. BPMP can serve as an effective therapeutic regiment to combat HTN in elderly male patients.

Keywords: Blood Pressure Management Program, BPMP, Panchakarma, Hypertension, Systolic, Diastolic, Mean Arterial Pressure, Elderly Male

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To Study Efficacy of Blood Pressure Management Program in Overweight to Obese Male Patients with Known History of Hypertension: A retrospective study http://madhavbaug.org/to-study-efficacy-of-blood-pressure-management-program-in-overweight-to-obese-male-patients-with-known-history-of-hypertension-a-retrospective-study/ http://madhavbaug.org/to-study-efficacy-of-blood-pressure-management-program-in-overweight-to-obese-male-patients-with-known-history-of-hypertension-a-retrospective-study/#respond Wed, 06 Mar 2019 18:18:44 +0000 http://madhavbaug.org/?p=7489 The post To Study Efficacy of Blood Pressure Management Program in Overweight to Obese Male Patients with Known History of Hypertension: A retrospective study appeared first on Madhavbaug.

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Original Article: To Study Efficacy of Blood Pressure Management Program in Overweight to Obese Male Patients with Known History of Hypertension: A retrospective study

Journal: International Journal of Ayurveda and Pharmaceutical Chemistry

Clinical Study: Int J Ayu Pharm Chem 2018 Vol. 9 Issue 1

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Journal Published Link: http://www.ijapc.com/volume9-first-issue/MNAPC-V9-I1-65-p-412-425.pdf

Abstract

Background and Objective: Hypertension is the leading cause of global burden of cardiovascular disease. It is an epidemic that globally affects one billion people and a common cause of death. This retrospective study was conducted in April 2017 to evaluate the effect of the Blood Pressure (BP) Management Program in overweight to obese category male hypertensive patients.

Methods: Data of 28 patients were included who had received the scheduled 6 sitting of BP management kit in a span of 90 days. In this study, the variables [mean systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), Body Mass Index (BMI) and dependency of allopathic medicines] were assessed on day 1 to day 90 of the BP management program. Results: The mean SBP was significantly lower on day 90 (153.5 ± 9.6 mm Hg to 127.80± 10.23 mm Hg, (p<0.001). The mean DBP reduced significantly from day 1 (91.60 ± 9.13 mm Hg to 78.64 ± 6.92 mm Hg). The mean value of MAP was much lower on day 90 (112.21 ± 7.3 5mm Hg to 94.80 ± 7.44 mm Hg, p<0.01). The BMI was much lower from day 1 (27.47 ± 2.49 to 26.45 ± 2.21, P < 0.001). Patients dependent on allopathic medicines were lesser at 90 days.

Conclusions: The BP management program was efficacious in controlling hypertension in male patients that were overweight or obese.

KEYWORDS: Blood pressure management, Alternative medicine, Panchakarma, Ayurveda

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The Effect of a Polyherbal Oral Formulation in the Management of Essential Hypertension: An Open Label, Pilot Clinical Study http://madhavbaug.org/the-effect-of-a-polyherbal-oral-formulation-in-the-management-of-essential-hypertension-an-open-label-pilot-clinical-study/ http://madhavbaug.org/the-effect-of-a-polyherbal-oral-formulation-in-the-management-of-essential-hypertension-an-open-label-pilot-clinical-study/#respond Wed, 06 Mar 2019 18:06:49 +0000 http://madhavbaug.org/?p=7486 The post The Effect of a Polyherbal Oral Formulation in the Management of Essential Hypertension: An Open Label, Pilot Clinical Study appeared first on Madhavbaug.

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Original Article: The Effect of a Polyherbal Oral Formulation in the Management of Essential Hypertension: An Open Label, Pilot Clinical Study

Journal: International Journal of Basic & Clinical Pharmacology (IJBCP)

Clinical Study: www.ijbcp.com, July 2018 | Vol 7 | Issue 7 Page 1427

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Journal Published Link: http://www.ijbcp.com/index.php/ijbcp/article/view/2566/2007

Abstract

Background: Effective control of blood pressure in patients with hypertension decreases cardiovascular mortality. However, many hypertensives are unresponsive to standard antihypertensive treatment. Research has found antihypertensive potential in the Ayurvedic drugs Brahmi (Bacopa monnieri) and Shunthi (Zingiber officinale). Hence, a pilot study was conducted to evaluate the efficacy and safety of Capsule Artyl (the oral formulation of Brahmi and Shunthi) as a treatment option in hypertensive subjects.

Methods: There were 30 hypertensive subjects attending out-patient departments of clinics in Maharashtra, India were enrolled in this four-week, open label, single arm study. All subjects received capsule Artyl (500mg) twice a day orally daily. The mean systolic (SBP) and diastolic blood pressure (DBP) on days 1 and 28 of the study were compared along with the mean arterial pressure (MAP).

Results: The mean SBP was significantly lesser on day 28 (141.86±12.54mm Hg) as compared to the mean SBP recorded on day 1 (155.48±19.37mm Hg) (p<0.001). The mean DBP on day 28 (89.66±6.8mm Hg) was lesser than that on day 1 (90.34±7.44mm Hg) but this difference was not statistically significant (p>0.05). There was a significant decrease in the mean value of MAP on day 28 (107.06±7.03mm Hg) as compared to that on day 1 (112.06±10.75mm Hg) (p<0.01).

Conclusions: Capsule Artyl significantly decreased the BP in hypertensive patients, without any adverse effects. Controlled trials are needed to confirm the positive outcome of this promising herbal formulation in hypertensive patients.

Keywords: Capsule artyl, Essential hypertension, Systolic blood pressure

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Efficacy of Ischemia Reversal Program (IRP) in Elderly Patients of Ischemic Heart Disease with Known History of Hypertension http://madhavbaug.org/efficacy-of-ischemia-reversal-program-irp-in-elderly-patients-of-ischemic-heart-disease-with-known-history-of-hypertension/ http://madhavbaug.org/efficacy-of-ischemia-reversal-program-irp-in-elderly-patients-of-ischemic-heart-disease-with-known-history-of-hypertension/#respond Wed, 06 Mar 2019 17:47:00 +0000 http://madhavbaug.org/?p=7479 The post Efficacy of Ischemia Reversal Program (IRP) in Elderly Patients of Ischemic Heart Disease with Known History of Hypertension appeared first on Madhavbaug.

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Original Article: Efficacy of Ischemia Reversal Program (IRP) in Elderly Patients of Ischemic Heart Disease with Known History of Hypertension

Journal: Asian journal of Cardiology research

Clinical Study: 1(1): 1-8, 2018; Article no.AJCR.43618

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Journal Published Link: http://www.journalrepository.org/media/journals/AJCR_123/2018/Dec/Mandole112018AJCR43618.pdf

Abstract

Context: The prevalence figures of major cardiovascular diseases (CVDs)- Ischemic heart diseases (IHD) and Hypertension (HTN) have escalated to epidemic levels, in both developing and developed countries. Ischemia Reversal Program (IRP) is a combination of Panchakarma and allied therapy.

Aims: This study was conducted to evaluate the effect of IRP on VO2max, Duke’s Treadmill Score, systolic blood pressure (SBP), diastolic blood pressure (DBP) in IHD patients with known history of HTN.

Setting and Design: This observational study was conducted from January 2017 to January 2018, wherein the data of IHD patients (inducible ischemia on stress testing) with history of HTN, who attended out-patient departments (OPDs) at Madhavbaug clinics in Maharashtra, India were identified.

Materials and Methods: Data of patients who were administered IRP (60-75 minutes) with minimum 7 sittings over 90 days (± 15 days) were considered. Variables were compared between day 1 and day 90 of IRP.

Results: Out of 30 enrolled patients, 24 were males while 6 females. There was a significant improvement in Duke’s score with subjects at moderate (43.3 %) and high (46.7 %) risk at baseline were significantly decreased to low (50 %) and moderate (50 %) after 90th day of therapy. IRP also showed significant improvement in VO2max from 18.14 ± 7.82 to 27.88 ± 7.31; p<0.001), SBP from 133.5 ± 16.36 to 121.87 ± 11.67, p< 0.004), DBP from 79.53 ± 8.53 to 75.3 ± 8.09, p<0.05). Dependency on concomitant medicines was reduced. Number of patients not taking any conventional medicine increased from 10% at day 1 to 27% at day 90 of IRP.

Conclusion: IRP was effective in management of elderly IHD patients with history of hypertension; it had triple benefits i.e. anti-ischemic effect, as well as reducing the blood pressure and reducing the dependency on conventional medications, which carries favourable prognosis.

Keywords: Ischemia reversal program; IRP; Panchakarma; ischemic heart disease; IHD; blood pressure; hypertension.

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Evaluation of the efficacy of Ischemia Reversal Program (IRP) in patients suffering from Ischemic Heart Disease (IHD) with known history of Hypertension: A Retrospective Study http://madhavbaug.org/evaluation-of-the-efficacy-of-ischemia-reversal-program-irp-in-patients-suffering-from-ischemic-heart-disease-ihd-with-known-history-of-hypertension-a-retrospective-study/ http://madhavbaug.org/evaluation-of-the-efficacy-of-ischemia-reversal-program-irp-in-patients-suffering-from-ischemic-heart-disease-ihd-with-known-history-of-hypertension-a-retrospective-study/#respond Wed, 06 Mar 2019 15:07:57 +0000 http://madhavbaug.org/?p=7459 The post Evaluation of the efficacy of Ischemia Reversal Program (IRP) in patients suffering from Ischemic Heart Disease (IHD) with known history of Hypertension: A Retrospective Study appeared first on Madhavbaug.

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Original Article: Evaluation of the efficacy of Ischemia Reversal Program (IRP) in patients suffering from Ischemic Heart Disease (IHD) with known history of Hypertension: A Retrospective Study

Journal: Journal of Ayurveda Medical Sciences

Clinical Study: J Ayu Med Sci 2018; Apr-Jun 3(2): 377-83.

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Journal Published Link: https://www.jayumedsci.com/article/2018/3/2/105530jams2018317

Abstract

Introduction: Cardiovascular mortality has risen in the last few years and Ischemic Heart Disease (IHD) is one of the most common causes. Ischemia Reversal Program (IRP) kit uses a combination of Snehana (Centripetal oleation), Swedana (Thermal vasodilation) and Basti (Per rectal drug administration) for providing relief to IHD patients. This study was conducted to evaluate the efficacy of IRP in IHD patients. Methods: This retrospective study included data of patients having positive inducible ischemia by stress test with known history of hypertension (HTN) and had visited the Madhavbaug clinics. A minimum of 7 IRP sittings were needed for inclusion. Duke Treadmill score, VO2 max, systolic plus diastolic blood pressure (SBP, DBP) and details of conventional medications were noted on day 1 and on day 90 followed by comparison between these values. Results: 19 patients having mean age 59.26 ± 8.03 years were enrolled, with 78.9% being males. On day 90, none of the patients were at high risk by Duke Treadmill Score, compared to 47.4% being at high risk on day 1 (p<0.01). Mean VO2 max significantly increased on day 90 of IRP therapy (p<0.01) while mean SBP and DBP decreased, though not significantly (p>0.05). The number of subjects on allopathic medicines decreased after 90th day, as compared to day 1. Conclusion: IRP treatment is associated with significant improvement in the Duke Treadmill score and VO2 max, thereby leading to betterment of prognosis in IHD patients. The dependency on conventional medicines was also decreased by IRP.

Keywords: Coronary artery disease, Duke’s Treadmill test, Ischemia Reversal Program, Myocardial ischemia

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To study the efficacy of Ischemia Reversal Program (IRP) in Ischemic Heart Disease (IHD) patients with VO2max and Duke’s Treadmill Score http://madhavbaug.org/to-study-the-efficacy-of-ischemia-reversal-program-irp-in-ischemic-heart-disease-ihd-patients-with-vo2max-and-dukes-treadmill-score/ http://madhavbaug.org/to-study-the-efficacy-of-ischemia-reversal-program-irp-in-ischemic-heart-disease-ihd-patients-with-vo2max-and-dukes-treadmill-score/#respond Wed, 06 Mar 2019 14:42:14 +0000 http://madhavbaug.org/?p=7447 The post To study the efficacy of Ischemia Reversal Program (IRP) in Ischemic Heart Disease (IHD) patients with VO2max and Duke’s Treadmill Score appeared first on Madhavbaug.

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Original Article: To study the efficacy of Ischemia Reversal Program (IRP) in Ischemic Heart Disease (IHD) patients with VO2max and Duke’s Treadmill Score

Journal: International Journal of Basic & Clinical Pharmacology

Clinical Study: August 2018 | Vol 7 | Issue 8

Click to Download Full Research Paper

Journal Published Link: https://www.ijbcp.com/index.php/ijbcp/article/view/2704

Abstract

Background: Number of people dying from IHD has increased from 0.61 million in 1990 to 1.13 million in 2010, which is a disturbing fact. According to report by World Health Organization, India would be spending a whopping 237 billion US dollars, owing to direct spending on health care and indirectly due to loss of productivity due to IHD. Ischemia Reversal Program (IRP) is a combination of Panchakarma and allied therapy. This study was conducted to evaluate the effect of IRP on VO2max, Duke’s treadmill score, systolic blood pressure (SBP), diastolic blood pressure (DBP), and dependency on conventional therapy in IHD patients.

Methods: This observational study was conducted in January 2017, wherein the data of IHD patients (inducible ischemia on stress testing) who attended out-patient departments (OPDs) at Madhavbaug clinics in Maharashtra, India were identified. Data of patients who were administered IRP (60-75 minutes) with minimum 7 sittings over 90 days (±15 days) were considered. Variables were compared between day 1 and day 90 of the IRP.

Results: Out of 38 enrolled patients, 25 were males while 13 females. There was significant improvement in Duke’s score with subjects at moderate (50%) and high (31.6%) risk at baseline were significantly decreased to low (52.6%) and moderate (47.4%) after the 90th day of therapy. IRP also showed significant improvement in VO2max by 9.11 (from 20.29±6.72 to 29.40±6.71; p<0.001), SBP by 5.78 (from 128.78±17.40 to 123±12.23, p<0.03), DBP by 4.76 (from 80.53±8.10 to 75.76±6.85, p<0.005). Dependency on concomitant medicines was reduced.

Conclusions: IRP was effective in IHD; it had dual benefits, i.e. anti-ischemic effect, as well as reducing the dependency on allopathic medicines.

Keywords: Alternative medicine, Blood pressure, Diastolic, Ischemia reversal program, IRP, Ischemic heart disease, IHD, Panchakarma

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To Evaluate the Efficacy of Heart Failure Reversal Therapy Using NT-Probnp Levels in Patients with Chronic Heart Failure http://madhavbaug.org/to-evaluate-the-efficacy-of-heart-failure-reversal-therapy-using-nt-probnp-levels-in-patients-with-chronic-heart-failure/ http://madhavbaug.org/to-evaluate-the-efficacy-of-heart-failure-reversal-therapy-using-nt-probnp-levels-in-patients-with-chronic-heart-failure/#respond Wed, 06 Mar 2019 14:33:11 +0000 http://madhavbaug.org/?p=7444 The post To Evaluate the Efficacy of Heart Failure Reversal Therapy Using NT-Probnp Levels in Patients with Chronic Heart Failure appeared first on Madhavbaug.

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Original Article: To Evaluate the Efficacy of Heart Failure Reversal Therapy Using NT-Probnp Levels in Patients with Chronic Heart Failure

Journal: Cardiology and Cardiovascular Research

Clinical Study: 2018; 2(3): 61-64 sciencepublishinggroup.com doi: 10.11648/j.ccr.20180203.13

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Journal Published Link: http://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20180203.13.pdf

Abstract

Heart failure is considered as a life-threatening epidemic disorder affecting about 26 million world’s population and associated with considerable morbidity, mortality and healthcare expenses. Despite the availability of a range of advanced treatments and sophisticated therapies the prevalence of heart failure represents a herculean challenge. To address the challenge, the current investigation was conducted by evaluating the efficacy of Heart Failure Reversal Therapy (HFRT) in reducing left ventricular distress by assessing N-terminal pro-brain natriuretic peptide (NT-proBNP) levels in congestive heart failure (CHF) patients. Total 76 CHF patients with NYHA Class II and III were screened from March to May 2017 and 15 CHF patients with NT-proBNP = 300-1500 pg/ml were selected for the study. NT-proBNP is measured as a marker, the value of which increases with an increase in severity of CHF. The study therapy, HFRT comprises of traditional procedure of panchkarma that includes snehana (external oleation), swedana (passive heat therapy), hrudaydhara (concoction dripping treatment) and basti (medicated enema) was administered twice daily for 7 days. Post-HFRT, ARJ kadha was administered for next 12 weeks follow-up. NT-proBNP levels were measured after a follow-up period of 90 days along with some other parameters like BMI, VO2peak (evaluated by cardiac stress test with modified Bruce protocol) and weight. The findings of the investigation revealed significant reduction in NT-proBNP levels (42.46%, p = 0.009), weight (4.82%, p = 0.0007) and BMI (3.67%, p = 0.034) at the end of the follow-up period. The study also yielded significant improvements in VO2peak (50.96%, p = 0.004). The overall results suggest that HFRT can possibly be explored as add-on therapy or a feasible alternative for the effective management of CHF.

Keywords: NT-proBNP, Chronic Heart Failure, Heart Failure Reversal Therapy

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To study the efficacy of Heart Failure Reversal Therapy (HFRT) Program in Elderly Male Patients with Reduced Ejection Fraction http://madhavbaug.org/to-study-the-efficacy-of-heart-failure-reversal-therapy-hfrt-program-in-elderly-male-patients-with-reduced-ejection-fraction/ http://madhavbaug.org/to-study-the-efficacy-of-heart-failure-reversal-therapy-hfrt-program-in-elderly-male-patients-with-reduced-ejection-fraction/#respond Wed, 06 Mar 2019 14:25:17 +0000 http://madhavbaug.org/?p=7440 The post To study the efficacy of Heart Failure Reversal Therapy (HFRT) Program in Elderly Male Patients with Reduced Ejection Fraction appeared first on Madhavbaug.

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Original Article: To study the efficacy of Heart Failure Reversal Therapy (HFRT) program in elderly male patients with reduced ejection fraction

Journal: International Journal of Medical and Health Research

Clinical Study: Volume 4; Issue 7; July 2018; Page No. 149-154

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Journal Published Link: http://www.medicalsciencejournal.com/archives/2018/vol4/issue7/4-7-15

Abstract

Background and Aims: Some authors consider heart failure (HF) to be a pandemic now, since nearly 26 million people have been affected by it, globally. Out of these, India alone has around 8-10 million patients. Heart Failure Reversal Therapy (HFRT) combines Herbal Panchakarma therapy with Dietary management. This study was conducted to evaluate the effect of HFRT on VO2peak, 6 Minute Walk Test (6MWT), systolic blood pressure (SBP), and diastolic blood pressure (DBP), BMI, weight, abdominal girth, and heart rate.

Setting and Design: This observational study was conducted from January 2015 to December 2017, wherein the data of elderly male patients with HF (NYHA class II and III) with reduced ejection fraction (<40%) who attended Madhavbaug hospital,
Khopoli, Maharashtra, India were identified.

Materials and Methods: Data of patients who were administered HFRT (60-75 minutes) with minimum 7 sittings over 7 days were considered. Variables were compared between day 1, 7, 30, 60 and day 90 of HFRT.

Results: 50 elderly males with HF and EF < 40% were enrolled in the study for analysis. There was significant improvement in VO2peak, from 12.71 ± 2.47 at baseline to 14.89 ± 2.05 at day 90 (p<0.001). 6MWT also showed significant improvement from 339.42 ± 106.85 at day 1 to 432.4 ± 89.27 at day 90 (p<0.001). Also, BMI, abdominal girth, weight showed similar statistically significant improvements. Improvements in SBP, DBP and HR were not statistically significant.

Conclusion: From the findings of our study, HFRT has been found to be a potent and viable therapeutic alternative for elderly male patients with HF with reduced ejection fraction.

Keywords: heart failure reversal therapy, HFRT, Panchakarma, heart failure, blood pressure, systolic, diastolic, VO2peak, 6MWT, NYHA

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