Abstract
Chronic ischemic heart disease (IHD) is a cardiovascular disease that results in an imbalance between the myocardial oxygen demand and supply. Despite several advances in medical science leading to a better understanding and management of IHD, this disease continues to be one of the worldwide leading causes of mortality. This necessitates the development of supplementary alternatives for the management of chronic IHD. This retrospective study evaluates the effectiveness of an ischemia reversal program developed by clinicians at Madhavbaug cardiac clinic and hospital by exploring its impact on the time to onset of ischemia through an evaluation of primary endpoints (maximum oxygen uptake capacity [VO2max] with the resultant metabolic equivalents of task [METs] and Duke Treadmill score [DTS]) and secondary endpoints [body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), and body weight] in patients with chronic IHD within the Mumbai region. Significant improvements in these primary and secondary endpoints indicated that the application of ischemia reversal program can delay the onset of ischemia and result in an improvement in the overall quality of life.






