Efficacy of Heart Failure Reversal Therapy (HFRT) Program in patients with Preserve Ejection Fraction: An Observational Study

Original Article: Efficacy of Heart Failure Reversal Therapy (HFRT) Program in patients with Preserve Ejection Fraction: An Observational Study

Journal: International Ayurveda Publications

Clinical Study: RESEARCH ARTICLE ISSN 2456-0170, Jul-Aug 2018 Vol III, Issue 4, Ayurpub.com

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Journal Published Link: https://www.ayurpub.com/wp-content/uploads/2018/10/1048-1058.pdf

Abstract

Background: Heart failure with preserved ejection fraction (HFpEF) is a worldwide healthcare issue showing growing prevalence, with complex management algorithms. Heart failure reversal therapy (HFRT) is a combination of Panchakarma and allied therapies used by Ayurveda physicians for CHF patients. This observational study was done to evaluate HFRT in HFpEF patients. Study was conducted between January 2017 to December 2017. The data of HFpEF patients who had been administered HFRT with minimum 7 sittings over 90 days (± 15 days) were considered. VO2max, metabolic equivalent (MET), body mass index (BMI), blood pressure (BP), dependency on conventional therapy were compared on day1 and 90. 28 patients were enrolled (21 males, 7 females) with a mean age of 55.79 ± 9.83 years. On analysis, there was significant improvement in mean VO2max (18.16 ± 5.71 vs 31.85 ± 4.80 ml/kg/min, p<0.01) and mean MET (5.19 ± 1.63 vs 9.10 ± 1.37, p<0.01) of the patients on day 90, when compared to day 1. Mean BMI (27.01 ± 3.98 kg/m2 vs 25.69 ± 3.21 kg/m2 , p<0.01) and mean SBP (129.64 ± 15.36 vs 118.79 ± 9.69 mm Hg, p<0.01) were decreased after 90-day HFRT therapy. Dependency on medications was also reduced.
To conclude, HFRT is effective in managing HFpEF patients and also decreases the dependency on allopathic medications.

KEYWORDS: Heart Failure Reversal Therapy, HFRT, Panchakarma, Chronic Heart Failure, Preserved Ejection Fraction, Ayurveda, Alternative medicine