Abstract
Type 2 Diabetes Mellitus (T2DM) is a syndrome characterized by a dysregulated metabolism and genetic immune-mediated involvement, and it progressively gets worse with the appearance of life-threatening complications and pathological changes that cause cardiac issues. A negative calorie balance with a low-carb diet is a very effective tool to manage T2DMwith a reduction in orally administered antihyperglycemic agents (OHA) support. As per the twin cycle hypothesis, negative calorie balance can reduce insulin resistance by the reduction in excess adipose tissue but in normal to low BMI T2DM, weight reduction is not advisable. So, the concept of a low-carb and low-calorie diet for good glycemic control is difficult to apply. This study aimed to evaluate impact of 240 ml of Sneha Basti (Myo B Basti: per rectal oil-based herbal formulation) along with an 800 cal/day (Prameh) diet to achieve good glycemic control in T2DM patients with low body mass index. The Myo B Basti shows a mean change of HbA1c in one month from 9.44 to 8.15mmol/mol. Myo B Basti was found to significantly improve HbA1c, BMI, body weight, abdominal girth, SBP, and DBP at the end of the study period i.e., 30th day. Allopathic dependency was also reduced to a great extent. Despite of an 800cal/day diet no major weight loss was observed. Thus, it can be concluded that Myo B Basti can be used as an efficient and safe therapeutic alternative for the treatment of T2DM.
Locate a Centre
