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Effect of Reverse Diet Kit on Regression of Atheroma in a Patient with Coronary Artery Disease: A Single Case Experimental Study

Effect of Reverse Diet Kit on Regression of Atheroma in a Patient with Coronary Artery Disease: A Single Case Experimental Study

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Abstract

Diet that maintains glycemic index and has high antioxidants might seize the progression coronary artery disease (CAD) in patients with diabetes. Impact of low calorie, high antioxidant food from reverse diet kit (12-week regime) in a 51-year-old CAD patient with diabetes is studied here. The reverse diet kit (RDK)contained pre-portion ready to cook food products that fulfil daily requirements of all mealtimes. Primary assessments: serum blood sugar levels and plaque characteristic changes determined by coronary CT angiography (CTA) at 12-weeks vs. baseline. Weight reduction of 9kg at the end of RDK intervention was observed. Blood sugar levels decreased significantly from 250mg/dl to 109mg/dl. A change of 124mm3 in total atheroma plaque volume (TAV) post-intervention vs. baseline was observed in four major arteries. The mean (SD) of TAV at baseline in LAD, LCX, and RCA (mm3) was found to reduce from 128.5, 98.5 and 381.1 to 113.7, 53.7 and 316.4 respectively. A clinically notable impact of
RDK viz. good glycemic control and reduced plaque volume at 12-week is seen in CAD patient with diabetes.

Aim:
The study aimed to analyse the impact of a low calorie, high antioxidantfood from reverse diet kit on the determinants of CAD progressionafter a 12 week follow up study in a patient with CAD and diabetes.

Objectives:

  1. To evaluate the effect of reverse diet kit on total atheroma volume (TAV) as assessed by coronary CT angiography (CTA) and changed dosages of concomitant medications
  2. To assess the change in weight, blood pressure, pulse rate, serum blood sugar levels, calcified and non-calcified plaque volume, calcium score, and calcium volume atthe baseline vs post-completion of the reverse diet programme for 12 weeks
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