Original Article: Efficacy of Ischemia Reversal Program (IRP) in Elderly Patients of Ischemic Heart Disease with Known History of Hypertension
Journal: Asian journal of Cardiology research
Clinical Study: 1(1): 1-8, 2018; Article no.AJCR.43618
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Journal Published Link: http://www.journalrepository.org/media/journals/AJCR_123/2018/Dec/Mandole112018AJCR43618.pdf
Abstract
Context: The prevalence figures of major cardiovascular diseases (CVDs)- Ischemic heart diseases (IHD) and Hypertension (HTN) have escalated to epidemic levels, in both developing and developed countries. The Ischemia Reversal Program (IRP) is a combination of Panchakarma and allied therapy.
Aims: This study was conducted to evaluate the effect of IRP on VO2max, Duke’s Treadmill Score, systolic blood pressure (SBP), and diastolic blood pressure (DBP) in IHD patients with a known history of HTN.
Setting and Design: This observational study was conducted from January 2017 to January 2018, wherein the data of IHD patients (inducible ischemia on stress testing) with a history of HTN, who attended out-patient departments (OPDs) at Madhavbaug clinics in Maharashtra, India, were identified.
Materials and Methods: Data of patients who were administered IRP (60-75 minutes) with a minimum of 7 sittings over 90 days (± 15 days) were considered. Variables were compared between day 1 and day 90 of IRP.
Results: Out of 30 enrolled patients, 24 were male, and 6 were female. There was a significant improvement in Duke’s score with subjects at moderate (43.3 %) and high (46.7 %) risk at baseline were significantly decreased to low (50 %) and mild (50 %) after the 90th day of therapy. IRP also showed significant improvement in VO2max from 18.14 ± 7.82 to 27.88 ± 7.31 (p<0.001), SBP from 133.5 ± 16.36 to 121.87 ± 11.67, p< 0.004), and DBP from 79.53 ± 8.53 to 75.3 ± 8.09, p<0.05). Dependency on concomitant medicines was reduced. The number of patients not taking conventional medicine increased from 10% at day 1 to 27% at day 90 of IRP.
Conclusion: IRP was effective in the management of elderly IHD patients with a history of hypertension; it had triple benefits, i.e. anti-ischemic effect, as well as reducing the blood pressure and reducing the dependency on conventional medications, which carries favourable prognosis.
Keywords: Ischemia reversal program; IRP; Panchakarma; ischemic heart disease; IHD; blood pressure; hypertension.
